The study further examined the impact of Goralatide on the proliferative activity of normal, remission, and leukemic progenitor cells, illustrating that under control conditions, erythroid progenitor cells are highly proliferative, with 38% of CFU-E and 30% of BFU-E cells in the S-phase of the cell cycle
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Nanoparticles were diluted in phenol red-free DMEM/HAMs F-12 medium (Gibco, Life Technologies, Carlsbad, CA, USA) supplemented with 5% FBS at a final concentration of 100 g/ml and added to the donor compartment (0.2 ml)
[17] Azathioprine treatment is associated with an increased risk of lymphoma, but whether this is due to the drug or a predisposition related to Crohn's disease is unclear