The NF-B pathway functions as a central pro-survival and pro-inflammatory transcription factor that promotes tumor progression by suppressing tumor suppressors such as phosphatase and tensin homolog (PTEN), thereby indirectly enhancing PI3K/AKT signaling and supporting cancer cell viability
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After another washing step the supernatant was discarded, the cell pellet was collected in a 1.5 mL collection tube, snap-frozen in liquid nitrogen, and stored at 80 C until analysis
whichever, correlates with our finding
10.1016/j.plaphy.2005.01.007 3 AlmeselmaniM.DeshmukhR