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It has been proposed that the western diet-induced intestinal ecological dysregulation and the altered intestinal barrier function can induce neuroinflammation, in turn can activate Toll-like receptors, then cause a proinflammatory response and the intestinal glial activation, ultimately contributes to the -synuclein pathology in the pathogenesis of PD (129)

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The Japanese experience with basic fibroblast growth factor in cutaneous wound management and scar prevention: a systematic review of clinical and biological aspects