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The slow intravenous infusion protocols used in clinical trials minimized these effects, suggesting that rapid bolus administration (which is essentially what subcutaneous injection creates) may increase the likelihood of transient side effects

[DOI] [PubMed] [Google Scholar] 24.Afaq F, Abidi P, Rahman Q

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Lowered Zinc Levels: Long-term use of supplements has been linked to reduced zinc levels in the body, suggesting a need for monitoring or concurrent supplementation