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GSSG is then recycled back to GSH by glutathione reductase using NADPH

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[DOI] [PubMed] [Google Scholar] 21.Achari A.E., Jain S.K

Paracrine factors such as IGF-1, HGF and VEGF directly activate PI3KAkt and inhibit intrinsic apoptosis [27], while exosomal miR-21, miR-144-3p and miR-126 down-regulate PTEN , MAP3K9 and other DDR amplifiers, reinstating controlled follicle activation and reducing oxidative phosphorylation overload [21, 25, 62]