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This research showed that GSH supplementation of amino acids (including L-glycine) and micronutrients (including vitamin C, vitamin E, and magnesium), as well as specific dietary patterns (vegetarian, the Mediterranean diet, and the DASH diet) had the potential to raise glutathione concentrations, which in turn slowed the rate of tissue deterioration

Several studies support the use of L-arginine for increased blood flow, but only in certain populations

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With suitable conditions in hand, we prepared a range of aryl-fused BCHeps with varied substitution patterns to diversify the potential exit vectors of the system (and covering the three possible 2-naphthyl regioisomers), while incorporating key functional handles for further derivatization (up to 2-mmol scale) (Fig