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and 24 healthy volunteers (12 females, 12 males, mean age 40.5 years, range 3065 years)

Complex III can also generate O 2 and release it into the intermembrane space where the O 2 traverses through voltage-dependent anion channels (VDACs) into the cytosol and is converted into H 2 O 2 by SOD1

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This represents telogen effluvium triggered by rapid weight loss and potential nutritional deficiencies, not a direct drug effect

Methods Enzymol 414:266283