TB-500 separate (typically 4-8x 5mg vials for 4-week protocol)
Nissl bodies can reflect surviving neurons, and these neurons may dissolve and disappear under pathological conditions
You are using a highly advanced, validated delivery system (like liposomal) and understand its inherent variability
Hauser RA, Kremens DE, Elmer LW, Kreitzman DL, Walsh RR, Johnson R, Howard R, Nguyen JT, Patni R (2019) Prevalence of Dyskinesia and OFF by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and OFF: Novel Analyses of Diary Data from Gocovri Pivotal Trials
The fatigue tied to B12 deficiency is often a deep, ongoing exhaustion that rest does not fully relieve