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Another way for HBx to induce oxidative stress is the suppression of proteins indirectly involved in the antioxidant defence, as observed in HBx-transfected HepG2 cells for the inhibition of selenoprotein P (SeP) [276] and in HBV-transgenic mice for selenium-binding protein 2 (Selenbp2) [274]

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Franco and Cidlowski, 2012

GSH can be found in the mitochondria, nucleus, and cytosol of cells, as well as plasma and extracellular spaces like the fluid which lines pulmonary alveoli [22]