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The risk of gastrointestinal bleeding during acenocoumarol therapy in carriers of any of the CYP2C9 or VKORC1 variants was severely increased with exposure to weekly doses of acenocoumarol higher than 15 mg or the use of amiodarone or aspirin (62)

The mercaptan is derived from allicin, a compound found in garlic, and is connected to the thiamine molecule via a special sulfur-sulfur bond called a disulfide bond

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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Michalopoulos G.K

De plus, certains mdicaments et une prdisposition gntique peuvent accrotre la susceptibilit l'hyperpigmentation, ce qui en fait un problme complexe ncessitant des traitements cibls