Temperature proves most critical - every 10C increase doubles degradation rate, meaning room temperature storage (25C) degrades peptides 4-8x faster than refrigeration (2-8C) and dramatically faster than freezing (-20C or below)
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Its not really bad to be exposed to sunlight but at least have protection and be sure not be exposed at a long period of time
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Notably, pro-inflammatory genes such as Il13, Il5, Csf2 among others were consistently downregulated following melatonin treatment ( Figure 5C )