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4,5,8 The structural similarity between p53 DBD and that of its homologues p63 and p73 suggests that p28 could also bind to either p63 or p73 and potentially enhance the reported tumor suppressive activity of individual isomers 4,7,9 through a similar mechanism of post-translational stabilization that alters their ubiquitination

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Als2/alsin deficiency in neurons leads to mild defects in macropinocytosis and axonal growth