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In contrast, in a hypertensive nephropathy model, USP25 inhibited the TGF- signaling pathway by suppressing the ubiquitination process of Smad4, delaying renal fibrosis and protecting renal function[106]

Effects of silibinin and antioxidants on high glucose-induced alterations of fibronectin turnover in human mesangial cell cultures

population indicate a negative correlation between serum BL levels and PD incidence, with maximal protective effects observed at 10.84 mol/L (Su et al., 2024)

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15,16 On the other hand, TRX reductase (TRXR) utilizes NADPH as an electron donor to maintain the reduced form of TRX, which contributes to scavenge H 2 O 2 and reduce ribonucleotide reductase (RNR) for DNA synthesis