Oxidative stress also affects the renin-angiotensin-aldosterone system (RAAS), a hormonal system that regulates blood pressure and fluid balance [79]
doi: 10.1080/13880200902930407
Also, recent reports suggested that those with pre-existing conditions such as diabetes, hypertension, and pulmonary, cardiac, and kidney diseases are at a higher risk of developing a severe infection [20,21,22]
From above experiments, Carbopol is considered more suitable than HPMC as polymer / gelling agent
People with specific gastrointestinal problems, such as Crohns disease or celiac disease, or those who have undergone gastrointestinal surgery may have difficulty absorbing B12 from food and supplements