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(19) measured cortisol levels and found no significant change and these results were replicated in a study by Moro et al

Estrogens and spermiogenesis: New insights from type 1 cannabinoid receptor knockout mice

RTV impedes the enzyme cytochrome P450-CYP3A4, which is responsible for the metabolism of xenobiotics, and therefore RTV induces an increase in intracellular drug concentrations in the patient (Zeldin and Petruschke, 2004)

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