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Recent studies have shown that ferroptosis plays an important regulatory role in the occurrence and development of many diseases and has become the focus and hotspot of research on the treatment and prognosis improvement of related diseases (Fig

It appears to promote angiogenesis (new blood vessel formation) at injury sites, upregulate growth factor receptors, and modulate nitric oxide signaling

Last, it is relevant to note that independent of aging and age-related diseases, FOXO4-DRI may be of use against the progression, stemness and migration of malignant cancer

Stimulates collagen formation

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