The peptide may also enhance the expression of a neurotrophic factor in the CNS called brain-derived neurotrophic factor (BDNF), promoting neuronal survival and resilience against stress [8]
Tirzepatide engages GIP near the strength of the natural hormone but activates GLP-1 about 18 times more weakly than natural GLP-1. After accounting for protein binding in blood, the drug is roughly 20-fold GIP-forward and has no meaningful glucagon activity
Holzner, G., Stavrakis, S
Minimal side effects, making it a safe option for recovery and performance enhancement
That molecule, now known as GHK-Cu, has since been shown to influence the expression of more than 4,000 human genes, touching pathways involved in tissue repair, inflammation, antioxidant defense, nerve regeneration, and cancer suppression