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10.1016/j.mce.2012.05.005 58 IrreraN.PizzinoG.DAnnaR.VaccaroM.ArcoraciV.SquadritoF.et al (2017)

In another phase I trial of CB-839 and paclitaxel in triple negative breast cancer, patients receiving CB-839 and paclitaxel showed different extents of improvement from disease control to partial response with tolerable adverse effects [64]

CYTOSOLIC AND MITOCHONDRIAL ONE-CARBON METABOLISM GENERATES NADPH One-carbon metabolism integrates the amino acids serine and glycine into the folate and methionine cycles that participate in many diverse biological outputs, including nucleotide synthesis (see Chandel 2020c) and methylation reactions involved in epigenetics (see Chandel 2020d)

doi: 10.1054/JCPT.2000.18011

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