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Hormone therapy, particularly when used for anti-aging purposes, can carry risks such as increased incidence of certain cancers, cardiovascular disease, and other health issues

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Jacobson MM, Gardner AM, Handley CE, Smith MW, Christensen WF, Hancock CR, Joseph PV, Larson MJ, Martin CK, LeCheminant JD (2023) Body shape perception in men and women without obesity during caloric restriction: a secondary analysis from the CALERIE study

A population coverage analysis revealed that the selected epitopes could potentially cover 68.27% of the global population for MHC class I alleles and 84.74% for MHC class II alleles, ensuring broad immunogenic applicability (Fig