In a rat model of hyperthyroidism induced by levothyroxine sodium, total extract and large polar iridoid fractions of Scrophulariae Radix significantly decrease key enzymes involved in glycolysis and the tricarboxylic acid cycle under hypermetabolic conditions (103)
Nitric Oxide Modulation: The interaction with the NO system to protect endothelial tissue from oxidative stress and toxin-induced damage
Hickman MJ, Petti AA, Ho-Shing O, Silverman SJ, McIsaac RS, Lee TA, Botstein D
In a randomized clinical trial involving older adults, GlyNAC supplementation improved glutathione status while also improving markers of oxidative stress, inflammation, mitochondrial function, muscle strength, and walking speed.57 58 Additional studies have reported improvements in several other measures associated with healthy aging, though the overall body of evidence remains relatively small compared with more established uses of NAC.34 Pure Encapsulations delivers 1,800mg each of NAC and glycine per serving, making it one of the highest-dosed products in this guide
While some folks use injectable glutathione to lighten their skin or fade dark spots, theres limited evidence to support its effectiveness in changing skin pigment
