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5-Methyl THF serves as a methyl donor in the vitamin B 12 -dependent reactions catalyzed by methionine synthase, which remethylates homocysteine to methionine, regenerating THF

High Prolactin Levels (Hyperprolactinemia): Elevated levels of prolactin, a hormone produced by the pituitary gland, can suppress other reproductive hormones, leading to infrequent periods or their complete absence

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