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Epithalon is most studied for its relationship with telomerase, the enzyme involved in maintaining telomere length

Delta cell death in the islet of Langerhans and the progression from normal glucose tolerance to type 2 diabetes in non-human primates (baboon, Papio hamadryas)

Also studied for inflammation modulation, angiogenesis, and neural tissue protection

LL-37 LL-37 is an antimicrobial peptide with dual anti-inflammatory activity

In addition, genetic variants in genes encoding for GPXs have been associated with increased mortality from cardiovascular diseases (Zhang et al., 2014) and diabetes (Hamanishi et al., 2004)