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[3] Joseph Harding, PhD, and his lab at Washington State University were the initial developers of Dihexa

Statements Author contributions KS: Conceptualization, Software, Visualization, Writingoriginal draft, Writingreview and editing

Comprising a short chain of nine amino acids, DSIP is recognized for its role in modulating sleep-wake cycles, neuroendocrine function, and stress responses

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height: Each member of the treatment groups received an icv injection of scopolamine hydrobromide (70 nmof in 2 aCSF over a duration of 20 s) 20 min prior to testing followed by Dihexa (300 pmol in 2 aCSF), Hinge (300 pmol in 2 aCSF), or Hinge + Dihexa (300 pmol in 4 aCSF) 5 min prior to testing