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These results indicate that cagrilintides metabolic effects are receptor-dependent and that functional AMY1R/AMY3R signaling is essential for proper nutrient partitioning and energy balance regulation

Its akin to saying something like let vendors that produce high-quality but unapproved and scientifically unproven pharmaceuticals sell them without formal FDA approval because otherwise people will use risky counterfeits. It makes no sense

Reading Each Dose on the Ladder Trial and clinical protocols seek the lowest dose that keeps the relevant markers moving without unacceptable side effects