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BV efficiently suppresses photoaging mechanisms and can treat photodamaged skin (Han et al., 2017)

Potential concerns include local injection reactions, immune responses to copper, and theoretical risks from unintended growth pathway activation

Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits

Bleeding can happen from blood vessels that had to be divided during the operation or from the staple-line on the gastric sleeve

These combined results reiterate potentially broad, beneficial effects of NTAPP on hair growth (Supplementary Figure 3a)