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The most actionable approach is tracking the downstream markers that respond to glutathione status: oxidative stress markers, liver enzymes, methylation markers, and inflammation

Subsequently, cell counting was performed using an inverted microscope (Nikon, Japan)

Figure 5 Because CB-839 alone had a limited effect on cell proliferation and apoptosis, we examined whether the metabolic changes associated with this drug would sensitize the CLL cell lines and primary cells to the targeted therapeutics

One such approach involves encapsulating psoralidin in mucoadhesive surface-modified bilosomes

doi: 10.1126/scisignal.abj6915 111 NiuX