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As an example of the activity of LA in nonceliac digestive disease, LA was recently used to enhance recovery of ischemia-injured jejunum in a large animal model of intestinal ischemia/reperfusion injury (49)

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In an oncogenic context, the IGF family regulates a number of biological processes such as cancer cell proliferation, apoptosis, metabolism and protein synthesis, which are closely associated with the activation of PI3K/AKT signaling, which subsequently promotes the transcription of downstream pro-oncogenic target genes such as c-Myc and HIF-1 (77)

K., Yang, J

Source Ghent University, Merelbeke, Belgium