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The mice were specific pathogen-free (SPF) and about 8 weeks old, weighing 20 2 g

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Male C57BL/6 mice (68 weeks old) were randomly divided into different subgroups and anesthetized with 1.53% isoflurane, and a left abdominal incision was made to expose the pancreas

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[10] Gastrointestinal disturbances-including nausea, loose stools, and a transient fishy body-odor attributable to trimethylamine production from excessive carnitine and choline metabolism-occur in a minority of recipients and are usually self-limiting within 24 to 48 hours after injection