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The primary solvents, PG and VG, act as carriers for nicotine and flavorings, but when exposed to high temperatures, they decompose into reactive carbonyl compounds such as formaldehyde and acrolein, both of which are highly cytotoxic to hepatocytes [120, 121]

In addition, North Carolinas Attorney General Josh Stein announced in November 2021 that he is suing the Juul founders for their personal roles in Juuls marketing to youth, launching a statewide investigation into Puff Bar, retailers that sell flavored e-cigarettes, and e-cigarette distributors

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Retrieved May 1, 2025