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doi: 10.3389/fendo.2023.1265372 6

TB-500 is a peptide consisting of 43 amino acids

The rationale is that glucagon also increases energy expenditure and promotes hepatic fat mobilization, so a molecule that combines glucagons metabolic-rate effect with GLP-1/GIPs appetite-and-glucose control can, in principle, drive weight loss from both sides of the energy-balance equation at once