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Dopamine, which acts as a neurotransmitter in the CNS is well known to not cross the BBB [68] due to lack of specific transporter and active metabolism in brain endothelial cells

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doi: 10.2478/v10007-012-0005-2 15 CalissendorffJMikulskiELarsenEHMollerM

[DOI] [PMC free article] [PubMed] [Google Scholar] 392.Fan F., Yang L., Li R., Zou X., Li N., Meng X., Zhang Y., Wang X