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TB-500 is a synthetic peptide that has gained recognition for its potential therapeutic effects on tissue repair and regeneration [1]

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Across preclinical studies, Epitalon has shown: Telomerase activation and telomere extension: Via TRAP assays and fibroblast lifespan extension beyond the Hayflick limit Epigenetic remodeling: Reversal of chromatin aging, histone modulation, and gene promoter binding Redox homeostasis: Increased antioxidant enzymes (SOD, NQO1, catalase) and reduced ROS, lipid peroxidation, and DNA damage Circadian restoration: Upregulation of AANAT/pCREB, normalized melatonin and cortisol rhythms, and clock gene modulation in humans Cancer risk reduction: Reduced tumor multiplicity and delayed onset in HER-2/neu and colon cancer models

[DOI] [PubMed] [Google Scholar] 131.Cesar L.B., Gojkovic S., Krezic I., Malekinusic D., Zizek H., Vuletic L.B., Petrovic A., Pavlov K.H., Drmic D., Kokot A., et al