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As a result of overexpression GGCT, not only did the level of glutamate m + 5 decrease, but also the levels of downstream metabolites such as -KG m + 5, succinate m + 4, fumarate m + 4 and malate m + 4 in the TCA cycle were affected (Fig

doi: 10.1016/j.jemermed.2006.08.004 [PubMed] 21970774 Mullins ME, Vitkovitsky IV

Also, it significantly increases the half-life of the mRNA in IL-8 through its stabilization and the expression of the proinflammatory cytokines, which contain ARE-like elements in their promotor region [43,108]

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Hypokalaemia (Low Potassium): In rare cases of severe anaemia corrected rapidly, serum potassium levels can drop rapidly, leading to symptoms such as muscle weakness or an irregular heartbeat