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10.1016/j.bpc.2023.107060 244 RzeteckaN.MatuszewskaE.PlewaS.MatysiakJ.Klupczynska-GabryszakA

Gastrointestinal effects (nausea, vomiting, diarrhoea) commonly reported in incretin-class research Injection site reactions at subcutaneous administration sites Appetite suppression observed dose-dependently in metabolic research models Most events in published trials reported as mild to moderate and dose-dependent Handling Reconstituting 5-Amino-1MQ 5-Amino-1MQ is supplied as a lyophilised powder and must be reconstituted before use in laboratory protocols

Understanding the difference is the way to correctly interpret the scientific literature on both peptides and design experiments that will reflect their differences on a molecular basis

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Neutralization tests and IC 50 determination To test for neutralization of the nanobody, plaque reduction assays were performed