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DYRK1A overexpression decreases plasma lecithin:Cholesterol acyltransferase activity and apolipoprotein A-I levels

Objective methods for sleep disorders assessment in cirrhosis include the polysomnography test which stands as the gold standard for diagnosing sleep disturbances, but its practicality is hindered by high costs and patient compliance challenges

Other aspects of the blood brain barrier including integrity are also under circadian control

Immunotherapies appear such as the most valuable strategy and could lead to the emergence of a new type of senolytics in a near future

The formation of ice crystals during the freeze-thaw cycle can physically shred the delicate peptide chains, destroying the compound just as effectively as heat