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Excessive alcohol use can cause brain damage and degenerative conditions like Wernicke-Korsakoff syndrome, which can cause severe memory impairment and other cognitive deficits

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In an initial estimate of factors responsible for the global burden of disease, tobacco, alcohol and illicit drugs contributed together 12.4% of all deaths worldwide in the year 2000

Some patients develop lichenoid lesions that resemble OLP but have an identifiable trigger

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