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These investigations remain limited to mechanistic and molecular analysis , without drawing conclusions related to clinical outcomes

PMID: 38992135

doi: 10.1016/j.gtc.2019.05.001

Alcohol additionally activates stress pathways such as MAPK, NF-B, and JNK, further driving inflammation and cell death (24, 25)

A pyruvate-cysteine-glutathione system/glycine-ROS metabolic pathway is identified as the most key pyruvate-boosting metabolic pathway to increase ROS level that potentiates gentamicin killing in several bacterial pathogens 73