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Collagen-producing fibroblasts depend on adequate vascular supply to sustain their metabolic demand during active matrix synthesis, making angiogenesis a prerequisite for effective structural repair

B12 shots are particularly beneficial for individuals with difficulty absorbing B12 from food or supplements

Campagna MC, Taketa T, Correa AM, Sudo K, Blum MA, Wadhwa R, Komaki R, Lee JH, Bhutani MS, Weston B, Liao ZX, Rice DC, Swisher S , Hofstetter WL, Ajani JA

ACOEP Scientific Assembly, San Francisco, CA, November, 2016

Considering these two approaches together may be relevant particularly in cases such as chronic fatigue, recurrent infections or diabetic wounds