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49 Phase 3 trials SYNCHRONISE-1 (in people without diabetes) and SYNCHRONISE-2 (in people with diabetes) are ongoing to assess the efficacy and durability of weight loss with 3.6 and 6 mg doses over 76 weeks (clinical trial numbers NCT06066515 and NCT06066528)

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A possible mechanism to understand how Pycnogenol contributes to lower glucose blood levels could be that sugar absorption was slowed down in patients supplemented with Pycnogenol by inhibition of -glucosidase, the enzyme that disassembles starch (64)

Consult your prescriber if you're on any medication that requires precise timing