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Its cosmetic use is debated and not universally approved for skin whitening purposes

When substrate load exceeds the compensatory potential of MCS, metabolic distress ensues and MCS signaling becomes dysfunctional [208,209]

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According to ClinicalTrials.gov, several bimolecular combinations alongside the dual GLP-1/GIP agonist tirzepatide are currently under investigation in phase 2 trials including eloralintide (NCT06603571), an amylin receptor agonist