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Description

Besides their central importance for the catabolic turnover of macromolecules, lysosomes also fulfill a critical anabolic function by serving as a recruitment platform for the multisubunit nutrient-sensing and signaling mechanistic target of rapamycin complex 1 (mTORC1), a major driver of anabolic programs, such as protein and lipid biosynthesis 4,5

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2009 Feb 1;89(2):693S-696S

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