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The copper ion is integral to GHK-Cu's biological activity, serving as a cofactor in enzymatic reactions involved in collagen crosslinking and antioxidant defence mechanisms
Cells 13, 230.Google Scholar Leow, DMK, Cheah, IKM, Chen, L et al
In the multivariate analysis, l-carnitine administration (odds ratio [OR] 3.51, 95% confidence interval [CI] 1.239.99, p = 0.019) and baseline NIRS data of 0.07 mMmm (OR 5.21, 95% CI 1.6916.0, p = 0.0041) were found as independent significant factors
The therapeutic effects of these compounds in animal models and in vitro studies either in delaying motor symptoms, protecting against motor neuron loss and/or improving survival suggest that further studies should be performed to characterize abnormalities in energy metabolism in ALS and explore potential metabolic therapies