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In addition, mood abnormalities are common [2], particularly despair and anxiety [23], whereas 58.4% of Long COVID patients have cognitive impairment and 3451-78% have memory problems, particularly memory loss [2, 18, 22, 104, 108]

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Importantly, this catalytic tetrad is conserved among all the seleno-GPxs (GPx1, GPx2, GPx3, GPx4, and GPx6) characterized from human (Table 1

Additionally, as drug release from encapsulated nanoparticles might impact the stability of nanoparticles, more attention needs to be paid to drug release events such as burst release and leakage from nanoparticles

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