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Further experimentation involved Annexin V-fluorescein isothiocyanate/propidium iodide labeling and flow cytometric analysis, which suggested that AHK-Cu may have reduced the number of apoptotic DPCs, although this decrease was not statistically significant and thus not conclusively confirmed

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Ethics statement The studies involving human participants were reviewed and approved by The Ethics Committee of the Second Peoples Hospital of Lishui (Zhejiang, China)

Mitigation in the Increlex label is straightforward: administer with food, never on an empty stomach, monitor glucose during titration, and keep fast-acting carbohydrates available

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