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Relying solely on an exopeptidase is often too slow to fully degrade the gluten molecule before it reaches the small intestine and triggers an inflammatory response
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Ingredients- Carthamus Tinctorius (Safflower) Seed Oil, Ricinus Communis (Castor) Seed Oil, Caprylic/Capric Triglyceride, Squalane, Hydrogenated Ethylhexyl Olivate, Cocos Nucifera (Coconut) Oil, Cocos Nucifera (Coconut) Fruit Extract, Simmondsia Chinensis (Jojoba) Seed Oil, Tetrahexyldecyl Ascorbate, Hippophae Rhamnoides Fruit/Seed Oil, Linoleic Acid, Phospholipids, Phytosterols, Rosa Canina Fruit Oil, Vanilla Planifolia Fruit Extract, Hydrogenated Olive Oil Unsaponifiables, Gamma-Decalactone, Benzotriazolyl Dodecyl P-Cresol, Gamma-Nonalactone, Delta-Decalactone, Delta Dodecalactone, Gamma-Dodecalactone, Gamma-Undecalactone, Gamma-Nonalactone, Limonene
Regarding pyruvate, recent studies have shown that the activator protein 1 (AP-1) transcription factor component c-Fos regulates chondrocyte proliferation and differentiation by balancing pyruvate flux between aerobic and anaerobic glycolysis (51)
Furthermore, patient selection based on inflammatory biomarkers (like CRP in CANTOS) might be important for identifying responders
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