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This can result in a variation in levels of 1030% from day to day and up to 45% within 24 h

Why is subcutaneous injection the preferred method for SLU-PP-332

11 Recombinant human platelet-derived growth factor (rhPDGF-BB) and enamel matrix derivative (EMD) have demonstrated tissue regeneration when used adjacent to a previously diseased root surface

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Renal tubular necrosis, hypoglycemic coma and coagulation defects may also occur