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This is in line with the higher expression of the major mitochondrial fission GTPase, dynamin-related protein 1 (DRP1) 76 (Fig

BRET measurements were carried out in HEK293T cells co-expressing Nluc-fused mas-GsBP1, mas-GsBP2, mas-KB1753 (in D, E and F), mas-GRK RH (in G), or mas-PRG RH (in H), with either wild-type (WT) or constitutively active (QL) mutants of Gi3 (in D), Go (in E), Gz (in F), Gq (in G), or G13 (in H) fused to a YFP, as indicated

Tompkins et al

Similarly, overexpression of hACOX1 N237S in cultured rat Schwann cells induced apoptosis, and cell death was suppressed by NACA