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Metabolomics APAP-induced liver injury biomarkers summary It is well established that translation of metabolic biomarkers from animal studies to humans is challenging due to the species difference as well as the confounding factors in humans including diet, age, lifestyle, overall health, drugdrug interaction and others, all of which will influence the metabolome profile

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Similarly, ipamorelin decreased CUNS by 20%, reduced the expression of urea cycle enzymes, and improved nitrogen balance, albeit less efficiently than GH

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doi: 10.1021/jf104590u