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Moreover, since the inception of this study, multiple metabolic mechanisms promoting drug resistance have been suggested for 5FU treatment, including changes in amino acid metabolism 69,70 , serine and glycine metabolism 71,72,73 and glycolysis 74,75 , corroborated within our study and independently validating our findings

A number of SOD mimetics have been developed possessing antioxidant properties in vivo[99, 100] and their benefits have been identified in animal models [101]

The oral route tablets or capsules is genuinely effective for gastrointestinal applications specifically

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Nature 594 , 566571 (2021)