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Menstrual changes that have been anecdotally reported include: Irregular cycle timing or missed periods Heavier or lighter menstrual flow Changes in premenstrual symptoms Breakthrough bleeding between periods It is important to note that there is no official direct link established between tirzepatide's pharmacological mechanism and menstrual function

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Patients with pernicious anemia This autoimmune condition destroys intrinsic factor, the protein required for B12 absorption in the small intestine